磁性共轭聚合物修饰超薄六方氮化硼的固相萃取及其在食品新兴污染物分析中的研究

Considering that it is vital urgency to establish the analytical methods for emerging contaminants in food, this project is schemed to prepare magnetic conjugated polymers-modified ultrathin hexagonal boron nitride which possesses superior adsorption capacity toward emerging contaminants. Moreover, the adsorption universality and selectivity of adsorption materials as well as its adsorption mechanism will be studied in details. Combined with modern analysis technologies, innovative solid phase extraction methods and techniques will be proposed for the rapid separation and detection of emerging contaminants in food. Firstly, ultrathin hexagonal boron nitride nanosheets (h-BNNSs) with large surface area will be synthesized via optimized preparation method. Then, ultrathin h-BNNSs will be modified by the as-prepared magnetic conjugated polymers so as to boost the synergistic extraction of conjugated polymers and ultrathin h-BNNSs toward emerging contaminants. Its adsorption mechanism will be studied in details. Finally, novel solid phase extraction methods will be established for the safety assessment for emerging contaminants in food. This project will not only find out the novel functions of h-BNNSs, but also screen novel adsorption materials with superior adsorption capacity. Besides, it can promote the improvement of the food safety management system and enhance the competitiveness of China’s food industry in the international market.

针对食品中新兴污染物分析的紧迫需求，本项目拟制备出适用于食品中新兴污染物分析的萃取性能优异的磁性共轭聚合物修饰超薄六方氮化硼固相萃取材料，探寻萃取材料的萃取普适性和专属性，阐述其吸附机理，发展高效、高选择性的固相萃取新方法和新技术，结合现代分析技术，实现食品中新兴污染物的快速分离和检测。首先通过优化六方氮化硼纳米片（h-BNNSs）的制备方法，获取大比表面积的超薄h-BNNSs；然后将制备的磁性共轭聚合物修饰到h-BNNSs表面，促成共轭聚合物与h-BNNSs协同萃取新兴污染物的作用，研究其吸附机理。最后，结合现代分析技术，将建立的固相萃取新方法应用于食品中新兴污染物的安全评价。本项目不仅是对h-BNNSs新功能的探索，也是构建高效新型吸附萃取材料的新途径，而且更有助于推动我国食品安全管理体系的完善和提高我国食品工业在国际市场的竞争力。

针对食品中新兴污染物的结构特点，本项目设计制备出了具有优异吸附性能的磁性六方氮化硼纳米片（Fe3O4@h-BNNSs）、聚吡咯修饰的磁性六方氮化硼纳米片（Fe3O4@h-BNNSs@Ppy）及聚噻吩修饰的磁性六方氮化硼纳米片复合材料（Fe3O4@h-BNNSs@Pth）；以植物生长激素（PGRs）和苯氧酸类化合物（POAs）为目标物，探寻了各类吸附剂的吸附性能，对影响萃取效率的实验因素进行了具体的优化；随后，又对吸附剂和目标物之间的吸附机理进行了详细地研究；结合HPLC-MS/MS技术，发展了高效的磁性固相萃取新方法，实现食品中新兴污染物的快速分离和检测。