超声微泡造影剂介导靶基因治疗梗死性血管病及机制研究
基本信息
结项摘要
超声波破坏携靶基因微泡造影剂治疗是一种新型的无创性基因转移技术。基本原理为：超声破坏微泡造影剂后，其产生的空化效应或机械作用可使细胞膜通透性增加、直径≤7μm的微血管破裂，内皮细胞间隙增宽。靶基因可通过破裂的微血管和内皮细胞间隙到达组织细胞。用超声波在特定组织击碎微泡，将提高基因治疗的靶向性和疗效。.梗死性血管病是临床常见病与多发病。梗死性血管病的基因治疗是重要的研究方向。本实验采用不同声强及频率
项目摘要
项目成果
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数据更新时间：2023-05-31
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