基于无线供能的诊疗振动胶囊与肠道动力功能评价方法的研究

There is a high incidence rate in the general population of functional constipation, which seriously affects the life qulity of people. However, patients with functional constipation are less satisfied with traditional treatments, such as medication, surgery and so on. It has obtained some achievment of the research on the treatment of functional constipation by vibration capsule, but there are some shortcomings existing in the vibration capsule system, such as short operating time, single function, uncontrollable vibration process, and so on. On the basis of the existing research, it intends to explore and research a new method of the project for diagnosis and treatment of functional constipation, which centralized with diagnosis, treatment and curative effect evaluation. We will focus on the following aspects: 1) To research the intestinal motility of the human body and the evaluation of the function of intestinal motility; 2) To develop a vibration capsule system based on wireless energy supply, with the function of intestinal function inspecting, vibration therapy and the evaluation of curative effects; 3) To explore the relationship between intestinal vibration and induced intestinal peristalsis; 4) To study the related technologies which match the vibration of the vibration capsule with normal intestinal peristalsis of the human body. The completion of this project will provide innovative methods and means for the diagnosis and treatment of functional constipation. The research results will play an important role in the research field of the physical vibration therapy of functional constipation.

功能性便秘在普通人群中具有较高的发病率，严重影响人们的生活质量。然而功能性便秘患者对现有的药物、手术等传统治疗方法的满意度较低。虽然采用振动胶囊治疗功能性便秘的研究取得了一定的成果，但是现有振动胶囊系统存在工作时间较短、功能单一、振动过程不可控等不足之处。本项目拟在已有研究基础上，探索研究集诊查、治疗、疗效评估为一体的功能性便秘诊疗新方法。项目拟在以下几个方面进行研究：一是人体肠道运动规律的研究以及评估肠道运动功能方法的研究；二是研制基于无线供能的振动胶囊系统，该系统具有肠道功能诊查、振动治疗和治疗效果评估等功能；三是探索研究肠道内振动与诱发肠道蠕动之间的关系；四是研究使振动胶囊的振动与人体肠道正常蠕动相匹配的相关技术。本项目完成将为功能性便秘疾病诊疗提供创新的方法与手段，研究成果将在功能性便秘疾病物理振动治疗的研究领域发挥重要作用。

功能性便秘在普通人群中具有较高的发病率，严重影响人们的生活质量。然而功能性便秘患者对现有的药物、手术等传统治疗方法的满意度较低。虽然采用振动胶囊治疗功能性便秘的研究取得了一定的成果，但是现有振动胶囊系统存在工作时间较短、功能单一、振动过程不可控等不足之处。本项目在已有研究基础上，探索研究集诊查、治疗、疗效评估为一体的功能性便秘诊疗新方法。项目在以下几个方面开展了研究：一是人体肠道运动规律的研究以及评估肠道运动功能方法的研究；二是研制基于无线供能的振动胶囊系统，该系统具有肠道功能诊查 、振动治疗和治疗效果评估等功能；三是探索研究肠道内振动与诱发肠道蠕动之间的关系；四是研究使振动胶囊的振动与人体肠道正常蠕动相匹配的相关技术。通过动物实验验证了系统的可靠性和安全性，动物实验的结果表明，振动胶囊可以增加实验动物的肠蠕动和排便次数。相关研究成果在功能性便秘疾病物理振动治疗的领域具有重要的科学意义。