MicroRNA抗急性缺血性心律失常的研究
基本信息
结项摘要
急性缺血性心律失常是心脏猝死的主要原因,心肌缺血时过度表达和分泌的内源性内皮素-1（ET-1）在急性缺血性心律失常发生中起重要作用。我们设想抑制心肌缺血时内皮素的合成与分泌可能减轻急性缺血性心律失常。近年发现的microRNA（miRNA）是内生的、长度为19-25个核苷酸的广泛存在于真核细胞的小RNA，它可以结合于靶mRNA的3'非翻译区（3'-UTR），进而降解靶mRNA或抑制靶mRNA编码蛋
项目摘要
项目成果
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数据更新时间：2023-05-31
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