足踝支撑对膝关节的生物力学影响

Foot-ankle-knee complex plays a role in supporting human body and its movement. Clinical observations and research found that a proper foot support could alleviate the knee pain; while improper supports may lead to knee problems. The key point for understanding this issue is the load alignment and transfer mechanism with different foot supports. Due to the complicated and limited experimental methods, computational biomechanical models of lower limb complex, based on finite element approach are useful and complementary tool for such kind of studies. The existing computational models mainly focus on isolated foot-ankle or knee structures. Although these models have provided useful information for understanding of its biomechanics individually, such isolated model may influence the integrity of the entire structures and may not provide full understanding of the question. In this proposed study, we will develop a computational model of entire lower limb including foot, ankle and knee related structures to understand their interactions under different foot ankle supports and during different gait phases. A series of in vivo and cadaveric experiments will be conducted to understand the load transfer and motion under various supports. The experimental findings will be used for model setup and model validation. Further parametric studies will be conducted using the validated computational models to provide scientific fundamentals for foot support designs in footwear industry or rehabilitation fields.

足踝膝，作为一体，起着支撑人体及运动的作用。临床观察和研究显示，恰当的足踝支撑可以治疗或缓解膝关节疼痛，不适当的足踝支撑可能损伤膝关节。足底支撑影响足踝膝结构中力传导的具体方式，是理解这种现象的关键所在。由于实验研究的局限性，以有限元分析为基础的人体下肢生物力学模型成为研究的有用工具。现有的有限元模型对孤立的足、踝或膝关节的生物力学已经有了一定的研究，但是将具有天然联系的结构人为割裂，破坏了生理结构的完整性，影响模型的边界和加载条件，对结果构成影响。本课题将在实验研究的基础上，进一步建立人体下肢一体化生物力学有限元模型，以研究在步态不同时相及不同足底支撑条件下，足、踝和膝关节的生物力学及其相互作用。该研究将增进对人体下肢力传导的了解，量化足底支撑对膝关节的生物力学影响，为鞋子和康复辅具的科学设计提供理论基础。

恰当的足底支撑可以治疗或缓解膝关节疼痛，不适当的足底支撑可能损伤膝关节。足底支撑影响足踝膝结构中力传导的具体方式，是理解这种现象的关键所在。本课题建立实验及生物力学建模的平台，以研究在不同足底支撑条件下，足、踝和膝关节的生物力学及其相互作用。生物力学实验研究实验包括步态分析、足底应力分布测量、剪切力测量、肌电信号测量，及尸体实验。在实验研究的基础上，进一步建立人体下肢肌骨系统模型及有限元模型。本研究的主要贡献在于健全了系统的生物力学研究方法体系，综合运动分析、尸体实验和计算仿真三种主要研究途径，可提供较为全面的生物力学信息。量化了足底支撑与下肢生物力学，尤其对膝关节受力分布的相互影响和作用关系，为通过足底支撑设计对膝关节炎或疼痛的临床干预和康复提供基础的参考数据，为鞋子和康复辅具的科学设计提供理论基础。.发表论文28篇，其中SCI检索24篇，专著1部包括6个章节，培养研究生4名。