鸟嘌呤衍生物互变异构化及与嘧啶环的弱相互作用研究

A matrix-isolation FTIR experimental equipment was setted up to be used at 4K in neon matrix. According to the adjusted project, we investigated the reactions of metal atoms with ammonia molecules. Theoretical studies on the interaction between lithium atom and DNA-base have also been done.

采用低温基质隔离－福利叶变换红外光谱，结合同位素表示和理论计算，研究几种鸟嘌呤衍生物互变异构体结构，氢键以及和嘧啶环之间形成的堆积相互作用，并用激光诱导互变异构化和质子传递反应，探索与点突变之间的联系。通过实验和理论并重研究国际上尚未涉及的鸟嘌呤衍生物，这对了解ＤＮＡ的结构和基因突变有着重要的科学意义。