基于并行扫描探针刻蚀构筑聚合物刷复杂三维结构的研究

Patterned three-dimensional (3D) polymer brushes are extraordinarily important surface architectures in many fields including biology, medicine, chemistry, energy, materials, and electronics. However, the throughput of producing high-resolution patterned 3D polymer brushes, even with the most advanced state-of-the-art nanotechnologies, is still very low to date, which significantly hampers their in-depth fundamental studies as well as many applications. To address the challenge, this proposal aims for developing parallel dip-pen nanodisplacement lithography (parallel DNL), a scanning probe based method that utlitzies a large number of parallel scanning tips, to allow large-area fabrication of many kinds of high-resolution, chemically-functional, patterned 3D polymer brushes. The as-made patterned 3D polymer brushes will further be studied as etching resist for making patterned 3D gold structures. The success of this project will set remarkable foundation for the fundamental studies of polymer brushes and the applications of their 3D structures in the future.

聚合物刷三维纳微米表面结构在生物、医药、化学、能源、材料以及电子等领域具有广泛的应用前景。目前只能小面积逐个构筑三维结构，无法满足对三维结构进行大量平行实验的研究或者需要大面三维结构进行检测应用时的迫切要求。本项目意在开发一种基于扫描探针的并行刻蚀技术，名曰并行蘸笔纳米置换，实现在基底上大面积构筑多种功能的纳米级分辨率的聚合刷三维表面结构，并研究如何用聚合物刷三维表面结构做模板构筑无机三维结构，为以后对聚合物和其他材料三维结构的基础研究和应用奠定理论和方法的基础。

聚合物刷三维纳微米表面结构在生物、医药、化学、能源、材料以及电子等领域具有广泛的应用前景。目前只能小面积逐个构筑三维结构，无法高通量制备大面积三维结构来满足应用的要求。本项目开发了一种基于扫描探针的并行刻蚀技术—并行蘸笔纳米置换，可实现在基底上大面积构筑多种功能的纳米级分辨率的聚合刷三维表面结构。该方法的分子置换机理及关键影响因素已经被考察清楚，并将所制备的聚合物刷三维结构作为抗蚀剂制备了任意构型的三维金结构。除此之外，还将所制备的多组分的聚合物刷三维结构用于细胞可控粘附及智能定向。该研究为聚合物刷三维结构在微纳加工、生物医药、能源电子等领域的应用奠定了坚实的基础。