阻断泛素通路时Bcl-2蛋白形成复合体的生物质谱分析
基本信息
结项摘要
细胞中一些最重要的生命过程都是通过蛋白复合体来执行和调节的，但由于鉴定困难，大多数上述复合体都是未知的，近年来，生物质谱灵敏度的极大提高显著地促进了对具有生物学功能和治疗潜力的蛋白复合体的鉴定。本项目拟以此为主要手段对阻断泛素通路选择性诱发肿瘤细胞凋亡的关键机制；bcl-2蛋白形成复合体进行研究，阐明其组成、定位和作用机制。
项目摘要
项目成果
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数据更新时间：2023-05-31
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