连续床分子印迹分离技术的研究

A new high efficitive separation method-molecular imprinting was studied. Chitosan molecular imprinting resin was made for heavy metal ion, which enhanced adsorption capacity 2 times compared to normal chitosan resin. The chitosan molecular imprinting resin has been used in to remove heavy metal ions from wastewater from tannery factory in large scale. A new chiral molecular imprinting resin based on polyacrylamide was synthesized and the resin could enantioselective separate (s)-naproxen. An affinity chromatography model was established. A new matrix based on cyclodextrin for natural product purification was made and the new resin could be used to purify radix puerariae flavone with 95% purity and 80% recovery.

研究一种新的将连续床和分子印迹集成在一个过程中的分离技术即.连续床分子印迹。在壳厶墙涣纬闪彩保胧杷藕徒?属亲和配基，强化分子专一识别性，消除颗粒内扩散阻力，提高了.分离效率。研究蛋白质和连续床介质在空间大小和表面功能基团之.间识别机理，为新型壳聚糖连续床分子印迹亲和层析的应用奠定基.础。