儿童视空间注意发育及其与中文阅读学习关系的神经机制研究

Visual spatial attention plays an important role in cognitive learning ability of human being. Previous studies reported that some children have defects in their visual spatial attention. However, the relationship between visual spatial attention deficit and high cognitive learning ability are still poorly understood. The current study will follow the technical development of cognitive neuroscience. By combining the behavioral data, resting-state EEG, task EEG and task ERP, we will systematically explore the neural mechanism of attentional selection and suppression development and its relationship with Chinese reading ability in children. In the current study, we will investigate and compare the EEG/ERP under different tasks and conditions in normal children, ADHD children and normal adults. Based on the multimodal fusion analysis, we will concentrate on the biomarkers of spatial attention in children, and try to find the relationship between these attentional biomarkers and Chinese reading ability. We believe that our study will contribute to the understanding of the neural substrates of attentional development as well as the its function in high cognitive abilities. Our study will contribute to early identification of children with ADHD and with reading difficulty.

视觉空间注意与高级认知学习能力密切相关，行为学研究表明有些儿童发育过程中存在视觉空间注意缺陷，但是如何影响高级认知能力学习的神经机制尚不清楚。本课题紧跟认知神经科学技术最前沿，采用行为，静息脑电EEG，任务态EEG频谱分析和事件相关电位ERP相结合技术，系统探讨儿童的视空间注意选择/抑制发展的神经机制，及其在中文阅读学习中的作用。 通过精细设计的实验对照，对比不同注意任务下，正常儿童、注意缺陷多动障碍儿童和正常成年人的EEG频谱和ERP成分，来提取出反应儿童注意视空间发育潜在的脑电生物学标记，并探究这些注意的生物学标记和儿童中文阅读学习的关系。我们的研究将有助于理解注意的发展与人类高级阅读学习能力的关系，有利于注意缺陷儿童、注意缺陷引发阅读困难儿童的早期鉴别，具有深远实践价值。

视觉空间注意与高级认知学习能力密切相关，行为学研究表明有些儿童发育过程中存在视 觉空间注意缺陷，但是如何影响高级认知能力学习的神经机制尚不清楚。本课题紧跟认知神经 科学技术最前沿，采用行为，静息脑电EEG，任务态EEG频谱分析和事件相关电位ERP相结合技 术，系统探讨儿童的视空间注意选择/抑制发展的神经机制，及其在中文阅读学习中的作用。通过精细设计的实验对照，对比不同注意任务下，正常儿童、注意缺陷多动障碍儿童和正常 成年人的EEG频谱和ERP成分，来提取出反应儿童注意视空间发育潜在的脑电生物学标记，并探 究这些注意的生物学标记和儿童中文阅读学习的关系。我们的研究将有助于理解注意的发展与 人类高级阅读学习能力的关系，有利于注意缺陷儿童、注意缺陷引发阅读困难儿童的早期鉴别 ，具有深远实践价值。