基于纳米压电体的新型传感器在生物医学领域中的应用研究

In this project, via the manufacture of nanometer piezoelectric body, measure the piezoelectric properties, then on the basis of experiment, establish and develop force electric coupling gradient theory and high efficiency stable numerical simulation method, understand physical properties of piezoelectric nanowires and superlattice deeply, design and manufacture nano piezoelectric cantilever beam biological sensor, at the same time, optimizate electrical and acoustics performance, design and manufacture biomedical high frequency ultrasonic transducer. Through this project, acquire the theory and numerical methods of the prediction of performance of nanowires and superlattice and the optimization design criteria of new type nanowires piezoelectric sensor and superlattice ultrasonic transducer. Realize that make biochemical detection system miniaturization and simplification, analyze complex material timely and efficiently. Use the superlattice ultrasonic transducer in the area of eye initial segment structure disease, capillary blood test, tumor efficacy evaluation and the image navigation of surgery and micro injection, which conventional equipments can not set foot in.

本项目是通过制备纳米压电体，测量其压电性能，在实验基础上，建立和发展适合在纳米尺度下的力电耦合梯度理论以及高效稳定的数值模拟方法，深入理解与表征压电纳米线和超晶格的物理性能，优化压电纳米线的结构，设计并制造纳米压电悬臂梁生物传感器；同时对电极-压电超晶格-电极"三明治"叠层结构和电学、声学性能进行优化，设计并制备生物医学高频超声换能器。通过本项目，获得预测纳米线和超晶格性能的理论与数值方法及新型纳米线压电传感器和超晶格超声换能器的优化设计准则，利用纳米线压电传感器实现生化检测系统的小型化、简单化，还可以及时、高效的分析复杂物质成分，并将超晶格超声换能器用于眼前节结构疾病、毛细管血流检测、肿瘤药效评估、手术及微注射影像导航等常规设备无法涉足的领域。

本项目是通过制备纳米压电体，测量其压电性能，在实验基础上，建立和发展适合在纳米尺度下的力电耦合梯度理论以及高效稳定的数值模拟方法，深入理解与表征压电纳米线和超晶格的物理性能，优化压电纳米线的结构，设计并制造纳米压电悬臂梁生物传感器；同时对电极-压电超晶格-电极"三明治"叠层结构和电学、声学性能进行优化，设计并制备生物医学高频超声换能器。通过试验分析和数值模拟本项目，我们获得了预测纳米线和超晶格性能的理论与数值方法及新型纳米线压电传感器和超晶格超声换能器的优化设计准则，利用纳米线压电传感器实现了生化检测系统的小型化、简单化，还可以及时、高效的分析复杂物质成分，并将超晶格超声换能器用于眼前节结构疾病、毛细管血流检测、肿瘤药效评估、手术及微注射影像导航等常规设备无法涉足的领域。