新型轮烷、多聚轮烷和环糊精纳米管研究

The following results were obtained in the present project:1. It was found that the 1:3 (Guest:Host) inclusion complex can be formed between phenylbenylbenoxazole (PBBO),2,5-(4,4’diphenyl)1,3,4-oxadiazole (BBOD) andα-cyclodextrin. So far, several thousands of 1:1 or 1:2inclusion complexes of cyclodextrin were reported in the literature, while only three 1:3 inclusion complexes have been found.2. Our results show that several small molecules can form one-dimensional nanotube with cyclodextrins. Some characteristics of the formation of this structure were oncluded. It was noted that the works concerning the nanotube formed between small molecules and cyclodextrin is rather scarce.3. It was found, for the first time, that the remarkable fluorescence resonance energy ransfer (FRET) occurs between donor and acceptor within the one-dimensional nanotube. This is a new phenomenon concerning the energy transfer in the new kind of nanostructure.4. To design rotaxanes, 4 substituted 3H-indoles have been synthesized. The preliminary results indicate that these molecules can form rotaxanes spontaneously with cyclodextrin. 5. A molecular sensor, in which a 3H-indole fluorecent group was attached to a cyclodextrin molecule, has been synthesized.6. The physicochemical properties, especially the fluorescent properties of the substituted 3H-indoles have been extensively studied, which are closely related to the properties of the supramolecular structures as mensioned above.

本项目拟对轮烷、多聚轮烷和环糊精纳米管超分子体系进行研究。在已有工作基础上，搞清新型轮烷自发形成的原因及规律，并将合成3H-吲哚分子系列，制备并鉴定低聚轮烷，实现远嗑勐滞橹谢泛肿邮娜宋刂啤１鞠钅炕菇邮笛樯现な的承┤〈绶杂毽?环糊精可能形成的纳米管化合物并研究其应用前景。以上工作均具有重要的科学意义。