CB介导的GDNF对多巴胺能神经元保护作用的分子机制研究
基本信息
结项摘要
如何保护那些容易受到损伤而变性死亡的中脑黑质多巴胺（DA）能神经元一直是帕金森病治疗研究的热点之一。有研究认为，胶质细胞系源性神经营养因子（GDNF）能够通过促进DA能神经元中钙结合蛋白(CB)的表达而保护DA能神经元，但GDNF的这一作用机制尚不明确。本项目研究采用免疫荧光染色结合计算机图像分析、Western blot及Northern blot等方法，研究黑质DA能神经元发育过程中，与GDN
项目摘要
项目成果
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数据更新时间：2023-05-31
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