基于四配位有机硼高效发光材料的设计合成及其传感应用

Boron-containing organic conjugated heterocycles have a wide range of application prospects in the field of organic optoelectronic devices because of their unique photoelectric and physicochemical properties. After a systematic and in-depth literature investigation, we found despite the fact that the scientists have devoted themselves to a wide range of research interests in this field, however, the reports on the thin-film based fluorescence sensing are rarely explored. Therefore, based on the above considerations, four-coordinate organoboron complexes with non-planar structural properties were introduced into the design of thin film-based fluorescence sensors and their basic photophysical properties were studied systematically in order to realize fast and reversible sensing as well as develop a new strategy for the preparation of fluorescence sensing films. Specifically, a series of fluorescent active substances with tetracoordinate boron as the core unit were designed and synthesized. The basic photophysical properties in different states are compared and the general law of luminescence will be summarized. Combining the theory of supramolecular chemistry and the difference of physical and chemical properties of substrate surface, a variety of fluorescent films or arrays with molecular channels have been prepared and their sensing performance to typical hazardous chemicals or biological agents was investigated systematically. The design as demonstrated provides an effective strategy to improve the sensing performance.

含硼有机小分子及聚合物具有独特的光电特性和理化性质，有着重要的科学价值和应用前景。尽管研究者对四配位硼化合物研究广泛，但是对其薄膜基荧光传感方面的研究却鲜有报道。因此，本项目拟将具有非平面结构特性的四配位有机硼化合物引入到薄膜基荧光传感器的设计策略中来，利用其特殊分子构型可有效避免分子间紧密堆积的特点，制备出具有丰富孔道结构的高性能荧光薄膜，提出新的荧光传感策略。具体地，设计合成一系列以四配位硼为核心单元的荧光活性物质，考察其微环境效应，比较其在不同状态下的基本光学特性，总结出发光的一般规律。结合超分子化学理论，借助基质表面理化性质差异，制备出多种富含“分子通道”的荧光薄膜或薄膜阵列，系统考察其对典型危化品或生物制剂的传感性能，总结归纳薄膜传感性能对功能分子结构的依赖性，为提出薄膜基荧光传感创制新策略提供新思路。

含硼有机小分子及聚合物具有独特的光电特性和理化性质，有着重要的科学价值和应用前景。同时，近几年来，多重共振硼氮材料由于具有窄带发射、发光量子效率高、优异的光化学及热力学稳定性等突出性能，已在有机发光二极管等领域实现应用，但是对其传感性能的研究却鲜有报道。本项目以此为研究背景，围绕有机硼高效发光材料的设计制备、光物理性质及传感和光电应用展开系统研究，获得了一系列四配位有机硼、多重共振硼氮高效发光材料，并在该类材料的结构设计、制备、表征、性质调控、光/热稳定性、光电特性、器件性能等方面取得了一系列创新性的研究成果。（1）四配位有机硼化合物的发光调控及基于聚集诱导发光性质的敏化型氟离子荧光探针；（2）同时具有长波长和窄带发射的多重共振发光材料的外围修饰通用方法、材料合成与光电性能研究；（3）多重共振有机硼氮化合物的首次氟离子传感应用；（4）比色和荧光双模式分子识别系统实现对醋酸钯的特异性检测及一氧化碳细胞成像。基于上述研究，相关研究成果发表项目标注SCI论文4篇，申请国家发明专利3项，其中，已授权1项。综上所述，本项目的研究成果有助于提供有机硼功能材料的制备方法，为后续的薄膜基荧光传感器件、有机光电器件的发展具有极为重要的价值和意义。