regulation of hypothalamic-pituitary-thyroid (HPT) axis, hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS) on thermogenesis of brown adipose tissue (BAT) was investigated in Brandt's voles (Microtus brandti), Mongolian gerbils (Meriones unguiculatus) and hibernate Daurian ground squirrel (Spermophilus dauricus ) exposed to cold or short photoperiod. The results indicated that thermogenesis induced both by cold and by short photoperiod was regulated mainly by SNS. Although hormones both in HPT axis and HPA axis were involved in the regulation, the patterns and extent of their functions did in a different way in every species. The characteristics of BAT thermogenesis in small mammals and the differences of its regulatory mechanism were correlated with animals' preferred inhabitancies. Besides these, It is possible that other complicated factors participate in thermigenetic regulation of BAT in mammals induced by cold or short photoperiod. HPT aixs was activated in Daurian ground squirrel during hibernation and it was helpful to increase thermogenesis during arousal, but HPA axis was inhibited during hibernation and the inhibition of this axis to BAT thermogenesis was released.
不同生活习性小哺乳动物,暴露与实验模拟短光照或低温环境,探讨下丘脑-甲状腺轴,下丘脑-肾上腺轴的激素水平变化,松果体褪黑激素浓度及分泌变化,对动物个体水平,褐色脂肪组织细胞水平和分子水平产热的影响,阐明光周期与温度诱导动物产热的体液调节机理及不同物植鹊鹘诘奶卣?深入发展我国的生理生态学研究.
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数据更新时间:2023-05-31
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