Amenable toxicity bioassay methods are required for environmental impact assessment and safe standard development. Settlement and metamorphosis of the planktonic larvae are bottleneck in many benthic marine invertebrates and share similar mechanisms of development with higher organisms. This shows its potential in toxicity bioassay. In the present project, inorganic ions, an organophosphate pesticide and benzene et al. were chosen as reprentive pollutants for toxicity study in adult and larval invertebrates, scallops and a serpulid hydroid worm and the mechanism underlining toxicity to the larvae were explored. The result indicates that larval metamorphosis is more sensitive to inorganic ions than to volatile compounds contamination and that the pollutants meight effect through interfering with cellular signal transduction pathway. This provides scientific expertise for biomonitoring of the environment and understanding of mechanism controlling the larval metamorphosis.
生物毒性实验是评价公害和制定化学品安全浓度的重要依据,人们一直在寻求适当的毒性指标。浮游幼虫的变态对污染物具有特殊敏感性,又是底栖动物发育中的关键环节,故适于作为毒性实验指标。本项目将研究几种典型污染物对盘管虫幼虫变态的影响,并与现有毒性实验指标相比较,探讨其毒性作用机理,为建立以幼虫变态为指标的毒性实验方法提供依据。
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数据更新时间:2023-05-31
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