应用近场光学方法的微尺度多相界面物质扩散研究

Soft matter is a hot research area in the near two decades, among which the material diffusion behavior is an important subject but with few research results especially for the diffusion at microscale multi-phase interfaces. This proposal is aim at the research of the diffusion at the multi-phase interfaces formed by hydrogel and hydrophobic fibers as model system, characterized by means of near field optical microscopy. The contents include the following four aspects: the fabrication of hydrogel and hydrophobic fibers system with microscale multi-phase interfaces, the application of near field microscopy, the measurements of material diffusion at the interface at various conditions, and the discussion of the diffusion mechanism and theory exploration. The purpose of this proposal is on the developing of novel methods for the research of diffusion at multi-phase interfaces and finally providing deep insights of the new transport pathways in mammal and human bodies.

软物质是近二十年来的研究热点，其中物质扩散行为研究具有重要意义，然而目前针对微尺度多相界面上的物质扩散行为研究还很少。本项目拟以水凝胶与疏水性纤维丝之间存在的多相界面为模式体系，结合近场光纤光学技术开展微尺度多相界面上物质扩散行为的研究。研究内容包括微尺度多相界面模式体系的构建、近场光学设备的适用性改造、物质扩散行为及影响因素的观测和微观扩散行为机理的探索四个方面。最终为定量描述微尺度多相界面上的溶质扩散行为提供研究手段，为理解生命体系中的物质传输通路提供新思路。