谷氨酸脱羧酶DNA疫苗预防胰岛炎研究
基本信息
结项摘要
采用编码人ＧＡＤ６５和胰岛素原的基因构建ＤＮＡ疫苗，针对免疫调节环路的关键环节，从整体、细胞及分子水平探讨其预防ＮＯＤ鼠胰岛炎及１型糖尿病的免疫耐受机制和规律，有助于进一步揭示１型糖尿病的自身免疫发病机制，阐明特异性自身抗原ＤＮＡ疫苗诱导免疫耐受的机理，为探索１型糖尿病的早期防治方法开展新思路和新途径。
项目摘要
项目成果
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数据更新时间：2023-05-31
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