直接测序法筛查中国人2型糖尿病家系及群体GCK、HNF-1α基因突变及突变家系临床病理生理研究
基本信息
结项摘要
糖尿病目前已成为人类的第三大杀手，尤其是中老年人致残致死、生活质量下降的最主要疾病之一，其中绝大多数是由多基因作用和环境因素影响所致的常见型2型糖尿病。而多基因糖尿病的病因学及发病机理复杂，基因型与临床表型的联系更难，所以至今未取得突破性的进展。近年国外的某些单基因突变糖尿病（如GCK基因）研究发现其有一定的临床特点。本项目以目前两个常见的单基因突变-GCK和HNF为切入点，在不同临床特点的糖尿病
项目摘要
项目成果
{{i.achievement_title}}
{{i.achievement_title}}
暂无此项成果
数据更新时间：2023-05-31
其他相关文献
Influencing factors of carbon emissions in transportation industry based on CD function and LMDI decomposition model: China as an example
Influencing factors of carbon emissions in transportation industry based on CD function and LMDI decomposition model: China as an example
Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem cell transplantation
Everyone has a donor: contribution of the Chinese experience to global practice of haploidentical hematopoietic stem cell transplantation
Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators
Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators
The Role of Osteokines in Sarcopenia: Therapeutic Directions and Application Prospects
The Role of Osteokines in Sarcopenia: Therapeutic Directions and Application Prospects
Relationship between pulmonary function and indoor air pollution from coal combustion among adult residents in an inner-city area of southwest China
Relationship between pulmonary function and indoor air pollution from coal combustion among adult residents in an inner-city area of southwest China
吴松华的其他基金
相似国自然基金
中国人MODYx家系MODY候选基因突变的筛查与功能解析
原发性闭角型青光眼家系整理及候选基因的筛查和定位
胎儿先天性心脏病临床表型与家系基因突变表现型关联的研究
掌跖角化症一大家系突变基因的筛查定位及相应角蛋白功能的研究