蒽并磺化冠醚的合成、主客体键合及超分子组装

Sulfonated aromatic crown ethers have been novel macrocyclic host with highly guest binding ability in supramolecular chemistry. Functional-group-modification on the aromatic rings can dramatically enhance the binding and self-assembly of sulfonated crown ethers. Therefore this program designed three types of modified disulfonated crown ethers bearing anthracene moiety. Various characteristic methods were employed to investigated the host-guest complexation, amphiphilic assembly and construction of supramolecular polymer between these disulfonated crown ethers and cationic guests, which might display interesting materials property like reversible gelation, multistimuli responsive and self-healing. After the systematic research the sulfonated crown ethers would be developed as important macrocyclic compounds to be applied on soft materiasl.

磺化芳基冠醚是具有高效客体键合能力的一类新型大环主体。通过对磺化冠醚进行官能团修饰，可以拓展磺化冠醚的客体键合能力和自组装性能。本项目设计了三种结构类型的二磺化蒽并冠醚作为研究对象，包括两亲官能团修饰磺化冠醚和桥联二磺化冠醚。采用多种分析方法研究二磺化冠醚同一系列有机阳离子的键合作用、两亲性组装和超分子聚合物的构筑，并研究其可逆成凝、多刺激相应、自修复等材料性能。通过这些研究，最终实现磺化冠醚在材料学上的应用。

磺化冠醚是超分子化学中非常独特的大环主体，在水溶液中能对多种阳离子芳香客体有选择性键合作用。本项目从蒽并冠醚出发，合成了五种磺酸型蒽并冠醚和磺酸羧酸型蒽并冠醚，进一步通过核磁、紫外、单晶衍射等测试手段研究了磺酸型蒽并冠醚和磺酸羧酸型蒽并冠醚对客体分子的键合。结果表明，相比文献已经报道的苯并磺化冠醚和萘并磺化冠醚，蒽并磺化冠醚对多种阳离子芳香合体都具有更强的键合作用，相关的研究拓展了pai-受体大环的范畴，为开发具有多种识别功能和传感功能的分子传感器提供了新的途径。此外，本项目从磺酸型蒽并冠醚和磺酸羧酸型蒽并冠醚出发，拓展研究了磺酸羧酸型芳香配体和羧酸型芳香配体同金属离子的配位组装，这一部分的工作为后期超分子大环与金属有机框架领域的学科结合与交叉研究提供了研究基础和理论支持。