手性液晶印迹克酮酸菁比色探针构筑及其多元可视化检测重金属离子性能研究

Heavy metals have many threats to the health and living environment of human beings. Therefore, it is of great significance to develop and establish a highly sensitive detection method for trace heavy metal ions in the environment. Photonic crystal is artificial microstructures which are periodically arranged by different refractive index media. The photonic crystal displays the structural color which is visible to the naked eyes when the optical band distributes in the visible-light range. The present project intends to construct a colorimetric probe system of chiral liquid crystalline croconaine using ion imprinted recognition technology. The functional dyes interacting with metal ions is used to to change the refractive index of the material, to realize high sensitivity and selectivity visual detection of heavy metal ions. Through chemical modification, we can make a clear color change reaction for the detected heavy metal ions by the photonic crystal, so as to realize the quantitative detection of heavy metal ions. Furthermore, the selectivity and sensitivity of chiral liquid crystalline croconaine colorimetric probe are studied in depth. The study on the structure-activity relationship between heavy metal ions and imprinted probe will be performed. The relationship between the design of chiral liquid crystal imprinting probe and its selectivity and sensitivity will be explored. The mechanism of recognition of heavy metal ions by chiral liquid crystal imprinting probe is revealed. On the whole, a new accurate, fast and simple method for the analysis of heavy metal ions was established by using the chiral liquid crystal imprinted croconaine colorimetric probe for the multivariate visualization detection of heavy metal ions.

重金属污染会对人类健康和环境产生极大威胁，发展和建立高灵敏度检测环境中微量或痕量重金属离子的方法具有重要意义。光子晶体是由不同折射率的介质周期性排列而成的人工微结构，当光禁带位于可见光范围内，光子晶体会展现出肉眼可见的结构色。本课题拟采用离子印迹识别技术，构筑手性液晶印迹克酮酸菁比色探针体系，利用功能比色探针分子与金属离子相互作用改变材料的折射率，实现对重金属离子的高灵敏和高选择性可视化检测。我们通过化学改性使光子晶体对被检测重金属离子产生明显的变色反应，实现重金属离子定量检测。深入研究手性液晶印迹克酮酸菁比色探针的选择性和灵敏度，研究重金属离子与印迹比色探针之间的构效关系，探究手性液晶印迹比色探针的设计与选择性和灵敏度的关系，揭示手性液晶印迹比色探针对重金属离子的识别机理。通过手性液晶印迹克酮酸菁比色探针对重金属离子的多元可视化检测研究，建立一种新型准确、快速、简便的重金属离子分析方法。

重金属污染会对人类健康和环境产生极大威胁，发展和建立高灵敏度检测环境中微量或痕 量重金属离子的裸眼检查方法具有重要意义。本课题通过对识别单体进行有机合成设计构筑手性液晶印迹克酮酸菁和方酸菁探针体系，利用功能比色探针分子与金属离子相互作用改变材料颜色，实现对重金属离子的高灵敏和高选择性可视化检测。我们通过化学改性使光子晶体对被检测重金属离子产生明显的变色反应，实现重金属离子定量检测。深入研究手性液晶印迹克酮酸菁和方酸菁比色探针的选择性和灵敏度，研究重金属离子与印迹比色探针之间的构效关系，探究手性液晶印迹比色探针的设计与选择性和灵敏度的关系，揭示手性液晶印迹 比色探针对重金属离子的识别机理。通过手性液晶印迹克酮酸菁比色探针对重金属离子的多元 可视化检测研究，建立一种新型准确、快速、简便的重金属离子分析方法。