在硅表面引入有机膜的新方法

Silicon is the most widely used semiconductor. It will be very useful in microelectronic and bio-technique industries if stable organic film can be made on the silicon surface. With the support of this project, we have made outstanding progress on the control of the surface chemistry and the subsequent application. Hairpin design and electric potential control on the surface have been combined to achieve differentiation of single nucleotide polymorphism (SNP). This method is cost-effective, sensitive, and of high selectivity and stability. We have also proposed novel methods to chemically immobilize DNA and to pattern the surface with chemical characteristics on the silicon substrate. These findings have promising applications in bio-chip technology. During the period of the project, 10 papers have been published or accepted, 6 MS and 4 PhD have been offered to the students in the group, a second rank award is given by the Ministry of Education, the group leader is honored with the "Chang Jiang Professorship", a PhD thesis from the group is elected as one of the hundred outstanding theses in the nation, and a patent is applied. The project has fulfilled the plan successfully.

硅是最常用的半导体材料。在硅表面制作稳固的有机膜将会在微电子技术和生物技术中有重要的应用前景。本申请提出一种新的光化学方法在硅表面生长稳固、可控的有机膜的方法。这一新方法将会对微电子技术、纳米器件的研究和生物技术的发展起到重要推动作用。