大鼠骨骼肌肌浆网非核DNA结合蛋白的生理及病理意义
基本信息
结项摘要
Based on the verifying the existing of non-nuclear DNA binding proteins in skeletal muscle sarcoplasmic reticulum， the structure and function of non-nuclear DNA binding proteins were investigated.The effect of sarcoplasmic reticulum Ca2+ transpot（including uptake and release）and calcium homeostasis with the binding of the protein and extrinsic DNA was firstly tested. The mechanism was estimated.The physiological and pathophysiological significance of the protein was illuminated.
非核DNA结合蛋白的重要意义正日益引起人们的关注，但其结构和生物学功能尚待阐明。本翁庠谥な荡笫筮蛇山屑〗嬖谟蟹呛薉NA结合蛋白的基础上，旨在研究该蛋白的结构并首次提出开展该蛋白与外源DNA结合后对肌浆网钙摄入与释放功能和胞浆钙稳态的影响及其机频难芯浚圆鞲玫鞍椎纳砑安±硪庖濉
项目摘要
项目成果
{{i.achievement_title}}
{{i.achievement_title}}
暂无此项成果
数据更新时间：2023-05-31
其他相关文献
DNAgenie: accurate prediction of DNA-type-specific binding residues in protein sequences
DNAgenie: accurate prediction of DNA-type-specific binding residues in protein sequences
中药对阿尔茨海默病β - 淀粉样蛋白抑制作用的实验研究进展
中药对阿尔茨海默病β - 淀粉样蛋白抑制作用的实验研究进展
神经退行性疾病发病机制的研究进展
神经退行性疾病发病机制的研究进展
组蛋白去乙酰化酶在变应性鼻炎鼻黏膜上皮中的表达研究
组蛋白去乙酰化酶在变应性鼻炎鼻黏膜上皮中的表达研究
MK-FSVM-SVDD: A Multiple Kernel-based Fuzzy SVM Model for Predicting DNA-binding Proteins via Support Vector Data Description
MK-FSVM-SVDD: A Multiple Kernel-based Fuzzy SVM Model for Predicting DNA-binding Proteins via Support Vector Data Description
姜志胜的其他基金
相似国自然基金
t－pA与Fn结合的生理及病理意义
心肌线粒体通讯机制及病理生理意义
REGγ介导的p53蛋白降解机理及其病理生理意义
清醒非束缚大鼠中暑的病理生理反应及机制研究