不同形式人群大肠癌MSH6突变研究
基本信息
结项摘要
本课题在黑龙江省肿瘤医院等医院征得医生患者同意后收集散发、非典型及典型遗传性非息肉性大肠癌病例（HNPCC），并采集血样及术后病理块。对血样用SSCP初步筛查，用序列分析方法进一步研究散发、典型及不典型HNPCC患者MSH6突变的形式和频率。对发现的突变与发表的文献或网上数据进行比较。对新的突变病例用免疫组化方法分析其病理切片肿瘤组织，确定是否为病理性突变。同时对有MSH6突变的患者，用1：1病例
项目摘要
项目成果
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数据更新时间：2023-05-31
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