本研究首次将编码汉坦病毒胞膜糖蛋白G1、G2的M片段与IL-2的cDNA连接到真核表达载体中菇ㄈ诤霞暗ザ辣泶颎1G2.及IL-2的质粒载体,在体外转染细胞证实可高效表达并保持良好的生物学活性后,直接免疫小鼠,观察接种后免疫应答指标。用汉坦病毒攻击,观察DNA免叩谋;ぷ饔谩Tて谟肐L.-2共表达增强其免疫效果,为汉坦病毒DNA疫苗的研制提供依据。.
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数据更新时间:2023-05-31
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