逆流聚焦电泳仪的研制

Ｔhis study on Focusing Electrophoresis Chip is based on the principle of "current cleavage for focusing electrophoresis". The in-situ concentration effect during separation process can improve the conventional capillary electrophresis in the following features: The final sample zones obtained are shortened for one order of magnitude and the resolution capability is improved. The lower limit for detectable concentration can be lowered for one order of magnitude due to the increase of sample concentrations by focusing in the final zones. Both the length of separation channel and the working voltage can also be reduced for one order of magnitude respectively.

提出一种基于新的逆流聚焦电泳原理的新型分析技术并制成仪器，实现样品按迁移率大小而分离、聚焦和检测。具有聚焦浓缩，浓度检测限好，工作电压低，样品分离为固定焦点便于阵列化和现场标定，应用对象广，仪器体积小等特点，可为医药、生化科研及国防公安提供一种成本低廉、市场广大的新型电泳仪器。在现有各类电泳之外，开拓一个电泳新领域。