针对食品中环境有机污染物前处理的微纳结构材料研究与应用

In order to overcome the difficulties of determining multi -environmental organic pollutantsresidue in food samples, a proposal was presented to increse sensitivity and accuracy of assay for target compounds basing on the solid phase extraction using micro-devices prepared by packing novel sorbents, such as electrospinning nanofibers and conductive polymer nano- clusters. To obtain the high-adsorption-efficiency nanomaterials , the preparation of nanomaterials will be investigated for controlling morphology and the appearance chemical characteristics of them. The sorption of typic drugs on nanomaterials will be investigated to compare the effects of thire composition, modification, and molecular size and functional groups of target compounds on extraction efficiency. After adsorption model experiment, analyze and probe into adsorption mechanism, find the rule of the adsorption and desorption for target compounds lying on the factors: molecular composition, morphology, size of nanomaterials and exterior enviromental condition. Try to screen out the optimum functional materials by changing molecular composition and micro- and nano- structure. Develop assay system for food samples including sampling, conservation, and the pre -processing basing on the extraction of multi-environmental organic pollutants by use of nanomaterials as the sorbents coupled to modern analytical instrument. These studies can support technologies for researches and application on environmental pollution and control.

针对食品中环境有机污染物目标物含量低、背景复杂导致的检测困难，提出以电纺纳米纤维和导电高分子纳米簇为固相吸附提取介质，组装成固相提取器件进行样品前处理，以提高检测灵敏度和准确性。为研制出高效的固相提取材料,进行纳米材料制备工艺研究以控制材料表面形貌和表面化学性质，试验不同基质材料对代表性的环境雌激素、农药等目标物的吸附特性，比较研究材料成分、修饰方法和目标分子的大小及分子中的官能团等因素对吸附性能的影响。结合吸附模型验证，分析探讨不同吸附效果产生的机理，总结纳米材料分子组成、形貌、尺寸以及外界环境因素对目标物的吸脱附效率影响规律。力图从分子结构、纳米、微米结构等多层次优化筛选功能新材料，构建基于纳米材料的目标物高效吸附提取体系，结合光谱、色谱、质谱等现代分析技术，建立起含环境有机污染物的复杂食品样品的采样、保存、前处理及测定的分析检测体系，为环境污染与防治的研究及应用提供技术支持。

本项目研究目标已经完成。制备了聚苯乙烯（PS）、磺化聚苯乙烯-聚乙烯吡咯烷酮混纺纤维（HCX）、聚苯乙烯双硫腙（混纺纤维PS-DZ）、聚苯乙烯十二烷基磺酸钠混纺纤维（PS-SDS）、聚苯乙烯十二烷基硫酸钠（PS- SLS）、十二烷基苯磺酸钠（PS- SDBS）等6种纳米纤维，并对其进行了表征；建立了食品中的邻苯二甲酸酯（邻苯二甲酸二丁酯（ DBP）、邻苯二甲酸丁基苄酯（ BBP）、邻苯二甲酸-（2-乙基己）酯（DE- HP）、邻苯二甲酸二正辛酯（ DNOP） ），喹诺酮类抗生素（氟罗沙星、诺氟沙星、沙拉沙星、环丙沙星、奥比沙星）等几种分析方法，开发了用于纳米纤维固相萃取的加压装置，自动化的纳米纤维固相萃取设备和装置。撰写并发表了6篇论文，申请3项发明专利并获得授权。