Myc对NDRG2基因的转录抑制作用机制的研究
基本信息
结项摘要
本项目拟主要研究Myc对人NDRG2基因及其家族成员基因表达的调控方式和机制。研究内容包括确定Myc抑制NDRG2基因表达的关键元件；探讨Myc如何影响NDRG2启动子的活性；控制NDRG2基因表达的转录复合物的分离及转录抑制机制的研究；确定Myc是否调控其他NDRG家族成员的表达及其机制；研究Myc抑制NDRG2基因表达的生物学意义。作为次要及备选研究内容，本项目还拟根据已知的NDRG2启动子序
项目摘要
项目成果
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数据更新时间：2023-05-31
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