纤维素纤维点击功能化之高效通用平台的构建与评价

Fiber engineering is advocated as a golden key to pulp and paper industry change, and holds great potential for the development of cellulose fiber-based functional paper/hybrid materials. Click chemistry becomes a novel and powerful tool for the functionalization of cellulose-based materials because of their high yields, high selectivity, and exceptional tolerance towards a wide range of functional groups and reaction conditions．In this project, an academic idea is originally proposed to build an efficient and universal platform for fiber engineering. A green non-degrading approach to constructing an efficient and universal platform for cellulose fiber functionalization by designating the heterogeneous alkyne-modification of cellulose fibers in an aqueous or aqueous-alcohol medium as a breakthrough will be demonstrated. On this basis, the applicability of the developed universal platform will be evaluated through several typical postfunctionalization modification attempts based on click chemistry. The research results of this project will open a new technological path for the high-valued utilization of cellulose fibers and manufacture of functional paper.

纤维工程被倡导为制浆造纸工业变革的一把金钥匙，在开发纤维素纤维基功能纸/杂化材料方面拥有巨大潜力。点击化学以其高产率、高选择性以及对各种官能团和反应条件优异的耐受性成为纤维素基材料功能化新的有力工具。本项目原创性地提出构建纤维工程高效通用平台的学术思想。拟以纤维素纤维在水或水/醇介质中的非均相炔基修饰为突破口，实现纤维素纤维功能化的高效通用平台的绿色非降解构建。在此基础上，拟通过几种典型的基于点击化学的后功能化改性尝试，对所开发的通用平台的适用性进行评价。本项目的研究成果可为纤维素纤维的高值化利用和功能纸的制造开辟一条全新的技术路径。

点击化学以高产率、高选择性和条件温和等特点，使其在制备纤维素基功能材料方面具有显著优势。基于原创性提出的纤维工程高效通用平台的学术思想，设计了具有点击反应活性的纤维素纤维制备方案。本项目以非均相纤维素纤维点击功能化平台的绿色构建为中心，开发了亲核醚化、选择性氧化和席夫碱反应组合、接枝共聚、原位聚合等共计6种方案，成功制备出了具有点击反应活性的炔基化、叠氮化及环氧化纤维素纤维。研究了制备过程变数对点击活性基团含量的调控作用，表征了反应前后纤维素纤维的物理和化学变化。纤维素纤维点击平台的点击活性通过与对应模块的点击反应进行评价。已有平台可以与抗菌功能化模块反应实现纤维素纤维的抗菌功能化。研究成果丰富了纤维素纤维改性反应类型，拓宽了纤维素纤维功能化思路，并为纤维素纤维的高值化利用开辟了新路径。