植物激素脱落酸与周质微管联络的分子基础

The phytohormone abscisic acid (ABA) and dynamic microtubule cytoskeletons play important roles during many development processes and stress responses in plants. However, whether there is a potential link between ABA and microtubules and how the crosstalk is processed and work for plant growth remains unclear. In our previous research, we proved that ABA could inhibit cortical microtubule reorganization, and microtubule-associated protein (MAP18) is involved in the dynamic regulation of microtubule network mediated by ABA. In order to elucidate the crosstalk mechanism of ABA and microtubules, kinds of mutants chosen by bioinformatics analysis are to analyze ABA responses, microtubule dynamics and genes expression in root and pollen growth of Arabidopsis thaliana. What are expected is to put forward the molecular basis and to improve the signal network of ABA and microtubules on the basis of identify and uncover the function of the key components connected ABA and microtubules, and then provide new ideas in research of plant growth regulation and stress responses.

激素ABA与动态的微管骨架对植物的生长发育和胁迫应答具有重要意义。然而，活跃的ABA与微管是否存在对话及如何对话有待研究。我们在前期的研究中发现ABA具有抑制周质微管动态重组的作用，初步的分析结果显示微管结合蛋白MAP18参与ABA对微管网络的调节。本研究利用模式植物拟南芥丰富的突变体资源，从反向遗传学角度出发，借助生物信息学辅助分析，研究拟南芥根和花粉发育过程中ABA和微管的动态应答及相关基因的表达，探索ABA与微管联系的分子基础。预期能鉴定参与ABA和微管对话的关键作用元件，对其进行功能鉴定，提出ABA调节微管动态的分子依据，进一步完善植物ABA与微管信号调控网络的结构和功能，为研究植物的生长发育调控及胁迫应答提供新思路。

激素ABA与动态的微管骨架对植物的生长发育和胁迫应答具有重要意义。然而活跃的ABA与微管是否存在对话及如何对话从而调控植物的生长发育过程有待研究。本研究利用模式植物拟南芥丰富的突变体资源，从反向遗传学角度出发，借助生物信息学辅助分析，研究拟南芥目标突变体不同发育过程中ABA和微管的相互动态应答。结果表明在根和花粉管的伸长生长过程中内源外源ABA水平升高有助于稳定垂直于生长轴方向的周质微管，进而促进植物的伸长生长过程；微管结合蛋白MAP18是ABA与微管联络的分子元件之一，参与ABA与微管对话对植物生长发育过程的调控。本研究为深入解析ABA与微管联络的分子机制进而调控植物的生长发育及胁迫应答提供了新思路。