血小板生成素(TPO)通过结合并激活其受体c-Mpl从而引起一系列信号传导事件而成为巨核细胞发育及血小板形成中的主要调控因子。对利用酵母双杂交系统,以c-Mpl为诱饵蛋白以竦玫娜鲇胄藕糯枷喙氐鞍捉徊郊ㄑ芯浚范ㄓ隿-Mpl相互作用的蛋白及作用机制,进而较系统地了解c-Mpl信号传导途径及激励,为探讨造血细胞发育机制及在临床上的应用蛳禄?.
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数据更新时间:2023-05-31
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