神经的运动控制及假肢控制信息源研究

Background: Prosthesis can replace the defect hand of amputees to achieve some functions, but the accuracy of the prosthesis controlled by myloelectric signal is dissatisfied. In order to improve the accuracy of the prosthesis, new signal source must be found. .Objective: To discuss the possibility to use signals recorded by LIFEs implanted into peripheral nerves..Method: LIFEs were implanted into sciatic fasciculus to detect their recording and stimulating characters and biocompation. Then LIFEs were implanted into fasciculus of radial nerve, ulnar nerve and medial nerve of an amputee to detect the signals of different movements that were used to control hand electrical prosthesis..Results. NAPs were recorded with LIFEs in acute animal experiments. The result proved LIFEs have stable recording and stimulating characters. When LIFEs were implanted into sciatic fasciculus of rabbits chronically, the amplitude of signal recorded by LIFEs decreased and latency lengthened, but they all became stable in 3 month. The pathological examine proved LIFEs had a little damage to peripheral nerves. When LIFEs were implanted into fasiculus of radial nerve, ulnar nerve and medial nerve of an amputee, signals can be recorded. Signals were difference when the amputee performed different movements. The signals recorded by LIFEs can be used to control hand prosthesis..Significance: This study proved peripheral fasicular signals recorded by LIFEs can be used to control hand electrical prosthesis as a new signal source. Hand electrical prosthesis controlled by fascicular signals will move much accurately.

本项目主要研究：1.新的假肢控制信息源的特性;2.神经的运动控制原理及假肢控制信号源僭旒际?3.多自由度假肢的数学建模与运动分析方法;4.多自由度假肢智能控制方法与技术;5.16-27自由度假肢模拟装置。以上研究在理论和实用上都有重大创新和突破，对人脑运动刂蒲芯亢腿乱淮僦⒂屑笾匾庖濉