激光打印纸基特殊润湿性表面与润湿功能自修复研究

Lab-on-paper (LOP) has been applied widely in the fields such as analysis and detection, cells and circuit, biology and medicine, paper-based chips, and so on. As the basis of LOP, paper-based special wetting surface needs both constructing technology with high efficiency and performance with durability and stability. However, the existing methods have insufficient like low efficiency and negative effect to paper substrate for constructing paper-based special wetting surface. Moreover, the special wettability at paper-based surface is not durable in application. In this project, laser printing will be used to construct the paper-based surface with special wettability, and special wettability once lost can be self-healed through external stimuli such as thermal, press, etc. In this method, PDA@ODA microcapsules can be prepared using interfacial polymerization, and then the resultant microcapsules are mixed with toner to prepare functional toner. Based on the functional toner, laser-printing is used to construct the paper-based wetting surfaces. The influence of printing parameters on microstructure and chemical composition of printed surface will be studied, and the relation between microstructure and chemical composition of printed surface and special wetting function will also be researched. Both results will be analyzed to clarify the physical and chemical mechanism of special wettability during laser printing. Moreover, the self-healing behavior of special wettability will be studied to reveal the self-healing mechanism of wetting function. This project is expected to propose a universal approach for constructing paper-based surfaces with special wettability and other functions such as antibacteria, antiflaming, and so on. Finally, the related theory and technique can be provided for developing various paper-based functional surfaces with self-healing capability.

纸基实验平台在分析检测、电池电路、生物医药、纸基芯片等领域具有广泛的应用前景。纸基特殊润湿性表面作为纸基实验平台的基础，既需要高效可控的构筑方法，又需要长效稳定的性能。本项目针对纸基特殊润湿性表面常用构筑方法效率低、易破坏等不足和特殊润湿功能易丧失的缺点，提出利用激光打印构筑纸基特殊润湿性表面，并通过热、压力刺激实现特殊润湿功能丧失后的自修复。该方法通过界面聚合法制备PDA@ODA微胶囊，并与商用碳粉混合作为功能墨粉；采用激光打印方法构筑纸基特殊润湿性表面；考察打印参数对纸基表面微结构和化学组成的影响，探明纸基表面微结构和化学组成与润湿功能之间的内在关系，阐明纸基表面润湿功能实现的物理化学机制；研究纸基表面润湿功能的自修复行为并揭示其自修复机理。本项目的实施有望为构筑纸基特殊润湿性表面和其它纸基功能（抗菌、阻燃等）表面提供一种普适性方法，为开发长效自修复纸基功能表面提供理论依据和技术支撑。

纸基实验平台在分析检测、电池电路、生物医药、纸基芯片等领域具有广泛的应用前景。纸基特殊润湿性表面作为纸基实验平台的基础，既需要高效可控的构筑方法，又需要长效稳定的性能。本项目针对纸基特殊润湿性表面常用构筑方法效率低、不可控、易破坏等不足，制备了三种适用于激光打印技术的超疏水功能墨粉，包括PDA@ODA-OA-Fe3O4功能墨粉，全氟辛基三乙氧基硅烷（PFOTES）改性功能墨粉以及十六烷基三甲氧基硅烷（HDTMS）改性功能墨粉，并利用激光打印技术将这三种功能墨粉分别打印在纸基表面构筑了纸基特殊润湿性表面。详细探讨了功能墨粉的微结构和组成成分对纸基表面润湿性能的影响规律，即纸基表面的打印区域粗糙度越大，其疏水性能越强，此外，适量的PDA@ODA-OA-Fe3O4微胶囊掺杂以及适量的PFOTES和HDTMS的接枝，有利于进一步提高纸基表面的疏水性能。同时揭示了利用功能墨粉激光打印获得纸基超疏水表面的物理化学机制，即微米级商用墨粉结合其表面的纳米级PDA@ODA-OA-Fe3O4微胶囊或纳米级颗粒形成了超疏水性能必须的粗糙结构，功能墨粉接枝的烷基链以及氟烷基链为纸基表面的超疏水性能提供了必须的低表面化学组成，基于此类粗糙结构和低表面化学组成，成功打印获得了纸基超疏水表面。另外，基于激光打印技术简单、快捷、可控的特点，利用激光打印方法将功能墨粉在滤纸表面打印了各种图案，并且快速、可控、批量化地打印了用于分析检测的单通道、多通道纸基微流控芯片，实现了金属离子的定性和定量检测。本项目的实施为研究激光打印用功能墨粉提供了一种思路，为构筑纸基特殊润湿性表面和其它纸基功能（抗菌、阻燃等）表面提供了一种普适性方法，为开发纸基实验平台提供了理论依据和技术支撑。