以水中抗生素污染物的传感检测和吸附分离为导向的发光多孔MOFs材料合成与性能研究

Antibiotics are largely produced and widely used in China during the last decades, which cause a big concern about their negative impacts on human health and ecosystem, especially for ambient water. The development of effective materials for detection and removal of antibiotic pollutants in water is an urgent problem to be solved. In this research project, a series of luminescent porous metal-organic frameworks (MOFs) with desired pores will be prepared from the assembly of strongly light-absorbing or light-emitting and hydrophobic amide carboxylate ligands with high-valent metal centers (such as Zr(IV), In(III), Eu(III) and Tb(III) etc.), by using antibiotic molecules or their structural analogs as templates. The free-template MOFs obtained by the heating, vacuum treatment or supercritical fluid extraction (SFE) method after solvent-exchange will be applied to selectively detect and adsorb antibiotic pollutants in water. The relationship between detecting/adsorbing properties and MOFs’ framework structures, shapes and sizes of pores, the types of adsorption as well as the host-guest interactions (π-π interactions, H-bonds etc.) will also be discussed. This study will not only provide new materials for detection and removal of antibiotic pollutants in water, but also prompt the development and integration of chemistry, materials and environmental sciences.

我国是抗生素生产和使用大国，每年有大量抗生素污染物被排放到环境水体中，开发一种快速检测、分离去除水中抗生素污染物的新材料是当前亟待解决的问题。本项目拟采用“分子模板”合成法，将含疏水基团的光功能酰胺羧酸配体与Zr(IV)、In(III)、Eu(III)、Tb(III)等高价金属组装，设计合成一系列具有特定孔道结构的水相中稳定的发光多孔MOFs新材料。利用低沸点溶剂交换“模板分子”后，通过加热、真空处理或超临界萃取等方法将其脱除；研究所得MOFs材料对水中抗生素污染物的选择性传感检测和吸附分离性能，探讨MOFs材料的骨架结构、孔道大小和形状、吸附类型以及主客体相互作用（如π-π作用、氢键）等对传感检测和吸附分离性能的影响，总结其结构和性能之间的构效关系，为环境水体中抗生素污染物的快速检测和分离去除提供科学依据。本项目对促进化学、材料和环境等学科的交叉融合具有重要意义。

我国是抗生素生产和使用大国，每年有大量抗生素污染物被排放到环境水体中，开发快速检测和分离去除水中抗生素等污染物的新材料是当前亟待解决的问题。本项目利用光功能有机羧酸配体与多种过渡、稀土和主族金属组装，设计合成了一系列具有特定结构的水相中稳定的发光MOFs化合物。通过加热、真空处理等方法脱除溶剂分子后，得到具有多孔结构的MOFs材料；研究结果表明该类MOFs材料对水中抗生素等污染物具有良好的选择性传感检测和吸附分离性能。结合实验数据和量化计算结果，深入分析了MOFs材料的骨架结构、孔道大小和形状以及主客体相互作用等对传感检测和吸附分离性能的影响，总结了其结构和性能之间的构效关系。本项目的研究，为环境水体中抗生素等污染物的传感检测和吸附分离提供了科学依据，也促进了化学、材料和环境等学科的交叉融合。