喹啉类含氮杂环化合物微生物作用过程中稳定同位素分馏

Microbial biodegradation has important influences on the environmental behavior and the fate of quinoline-like pollutants, and it also plays an important role in the natural bioremediation of these pollutants. Compound-specific stable isotope analysis (CSIA) has promising prospects for the study on the source identification, biotransformation and biodegradation mechanisms of organic pollutants. In this project, by using quinoline and its derivatives as the typical model compounds of nitrogenous heterocyclic compounds, CSIA is used to study the carbon and hydrogen isotopic fractionation effect and its influencing factors during their aerobic microbial biodegradation. The isotope fractionation factors of carbon and hydrogen will be determined for the biodegradation of quinoline and its derivatives. CSIA will also be used to learn the biodegradation mechanism of quinoline and its derivatives based on the isotopic fractionation of carbon and hydrogen. The bioremediation of the sites polluted by quinoline-like compounds will be qualitatively and quantitatively assessed by the CSIA method. This study will be important instructive for the bioremediation of the sites polluted by nitrogenous heterocyclic compounds, and it will also be important helpful for the comprehensive understanding of the transportation, biotransformation and fates of quinoline and its derivatives in the environment.

微生物降解是影响喹啉类污染物环境行为及归趋的重要因素，同时也是环境中该类污染物自然修复的重要作用。单体稳定同位素分析在环境中有机污染物来源识别、生物转化及降解机理等方面具有很好的应用前景。本项目以典型的含氮杂环化合物喹啉类污染物为研究对象，利用单体稳定同位素分析，开展喹啉类含氮杂环化合物微生物好氧降解过程中的碳、氢同位素分馏效应及其影响因素研究,确定喹啉类污染物微生物作用的稳定同位素分馏系数，探讨同位素分馏效应在喹啉类污染物降解机理中的应用，对污染场地喹啉类污染物微生物降解进行定性定量评价。该项研究对含氮杂环化合物污染地区的生物修复具有重要的指导意义，同时也对充分了解喹啉类污染物在环境中迁移转化及归趋具有重要帮助作用。