饮用水中新型极性环状结构卤代消毒副产物的检测鉴别、生成机制和控制原理研究

As emerging pollutants in drinking water, polar cyclic halogenated disinfection byproducts (DBPs) have been drawing increasing concerns as a result of their high toxicity and reactivity. However, due to the wide variety of structures, complexity of formation mechanisms, and difficulty of control, studies on polar cyclic halogenated DBPs were quite limited. This project was designed to study the identification, formation, and control of new polar cyclic halogenated DBPs in drinking water. With the aid of ultra performance liquid chromatography/ion trap-time of flight mass spectrometry as well as “standard compound synthesis + analytical chromatography qualification + preparative chromatography isolation + multi-dimensional characterization”, formula and structure identification methods for new polar cyclic halogenated DBPs will be developed, respectively. Based on multiple reaction monitoring using ultra performance liquid chromatography/electrospray ionization-triple quadrupole mass spectrometry, an optimized quantification method for new polar cyclic halogenated DBPs will be set up. Formation of new polar cyclic halogenated DBPs in combined contaminated drinking water will be investigated to elucidate their precursors and formation mechanisms. Furthermore, control principles for new polar cyclic halogenated DBPs will be developed based on “precursor reduction + formation suppression”. This project will provide new analytical methods and control principles for new polar cyclic halogenated DBPs in drinking water.

极性环状结构卤代消毒副产物作为饮用水中的新兴污染物，具有很强的毒性和反应活性，对饮用水安全造成极大威胁。然而，由于其种类结构繁多、生成机制复杂、控制削减困难，相关研究还处于起步阶段。本项目拟重点研究饮用水中新型极性环状结构卤代消毒副产物的检测鉴别、生成机制和控制原理。建立基于超效液相色谱/离子阱-飞行时间质谱的分子式鉴别方法和基于“标准品合成+分析色谱定性+制备色谱分离+多维度表征”的结构式鉴别方法，实现新型极性消毒副产物结构式鉴别方法从“微观分析”到“宏观表征”的突破。建立基于超效液相色谱/电喷雾三重四极杆质谱多反应监测的定量方法。在此基础上，系统研究复合污染型饮用水中新型极性环状结构卤代消毒副产物的生成条件，辨识前驱物、解析生成机制，进而构建基于“前驱物削减+消毒过程抑制”的控制新技术原理。本项目的工作将为饮用水中新型极性环状结构卤代消毒副产物的分析和控制提供新的科学方法和技术支撑。

极性环状结构卤代消毒副产物作为饮用水中的新兴污染物，具有极强的毒性和反应活性，对饮用水安全的威胁不容忽视。然而，由于其种类结构繁多、生成机制复杂、控制削减困难，相关研究还处于起步阶段。本项目重点研究了饮用水中新型极性环状结构卤代消毒副产物的检测鉴别、生成机制和控制技术。建立了基于超效液相色谱/离子阱-飞行时间质谱的分子式鉴别方法和基于“标准品合成+分析色谱定性+制备色谱分离+多维度表征”的结构式鉴别方法，实现了新型极性消毒副产物结构式鉴别方法从“微观分析”到“宏观表征”的突破。建立并优化了基于超效液相色谱/电喷雾三重四极杆质谱多反应监测的精准定量方法。在此基础上，系统研究了新型极性环状结构卤代消毒副产物的生成条件，辨识前驱物、解析生成机制，进而构建基于“前驱物削减+消毒过程抑制”的控制新技术。本项目的工作为饮用水中新型极性环状结构卤代消毒副产物的分析和控制提供了新的科学方法和技术支撑。