大肠杆菌O157:H7基因组中未知功能O岛的研究
基本信息
结项摘要
本项目将利用O157：H7大肠杆菌基因组的信息，对基因组中部分O岛的分布和功能进行研究。一方面揭示在不同来源的O157：H7大肠杆菌和其他肠杆菌科致病菌中O岛的分布特征，寻找O157：H7大肠杆菌特有的基因序列，发展快速的细菌鉴定指标，具有实际应用价值。另一方面对O岛进行毒力岛结构的特征化研究和边缘序列分析；利用一步PCR法缺失O岛的个别基因，对O岛的功能进行筛检研究；深入研究可能编码新的RTX毒
项目摘要
项目成果
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数据更新时间：2023-05-31
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