紫精衍生物金属有机凝胶的构筑及其在有机胺荧光传感中的应用

A serious threat to the environment and human health is emerging with significantly increasing of organic amines emissions which because of the rapid development of polymers, dyes and pharmaceuticals and other industries. Today, the sensing detection for organic amines has become the focus question in the fields of environmental monitoring, analytical chemistry, food quality monitoring and medical diagnosis and so on. For the typical electron-enriched organic amines, this project is first aimed to design a series of electron-deficient viologen-derivative ligands and then combined transition or rare earth metals to fabricate high stable fluorescent sensing coordination polymer gels with reversible solution-gel transformation characteristics and high selective recognition, sensitivity for specific organic amine molecules. This project will systematically investigate the effects of ligand, metal species and reaction conditions on the morphology, structure and luminescence properties, revealing the mechanism of coordination polymers gelling. Through the summarization of the effects of organic amine molecules on the color and intensity for the fluorescent coordination polymer gels, this project will illustrate fluorescence sensing mechanism with the combination of density functional theory. The project can achieve the controlled preparation of coordination polymer gels with the fluorescence sensing for specific organic amine molecules. In addition, the project can filter out light-color responsive materials for organic amines with high stability and high sensitivity for building a portable fluorescence sensing platform, achieving the direct, rapid, specific, and sensitive sensing analysis for specific organic amine molecules.

随着高分子聚合物、染料以及医药等行业的快速发展，胺类有机物排放量明显上升，给环境和人类健康带来严重威胁。目前，有机胺的传感检测已经成为环境监测、分析化学、食品质量监控以及医学诊断等领域关注的焦点问题。本项目针对典型富电子有机胺，拟设计制备一系列有缺电子特点的紫精衍生物有机配体，结合过渡或稀土金属构筑具有高稳定性、可逆溶液-凝胶转变特性，且对特定有机胺分子有高灵敏性、高选择性识别的荧光配位聚合物凝胶传感材料；考察配体结构、金属种类以及反应条件对材料形貌、结构和发光性能的影响规律，揭示配位聚合物胶凝化机理；总结有机胺分子对配位聚合物凝胶荧光颜色和强度的影响规律、结合密度泛函理论阐明荧光传感机理；实现针对特定有机胺分子荧光传感配位聚合物凝胶材料的可控制备；同时筛选出高稳定性、高灵敏性有机胺光色响应材料构筑便捷式荧光传感平台，实现对特定有机胺分子的直接、快速、特异、灵敏的传感分析。

金属有机框架材料在能源、荧光检测、电化学检测等众多领域引起广泛关注。在本项目执行过程中，开展了以下几个方面的相关研究：针对典型有机胺设计合成紫精羧酸衍生有机配体，结合过渡或稀土金属离子， 构筑对特定有机胺分子荧光传感响应的金属有机凝胶；构建磁性金属有机骨架材料富集肉制品中磺胺类化合物并进行高通量检测；构筑一系列基于金属有机框架衍生材料作为氧还原反应的非贵金属催化剂；构筑系列金属有机骨架及其衍生材料，进行相应待测物的荧光和电化学分析检测。考察了有机配体、金属中心、材料形貌等因素对电催化和检测的影响，对金属有机框架材料在能源和光、电化学分析中的实际应用有指导意义。